The bacterium Mycoplasma genitalium MG is sexually transmitted and can cause inflammation of the urinary and genital tracts in men and women. This germ may also be linked to other problems, including some cases of arthritis and, in women, pelvic inflammatory disease and infertility. MG appears to be spread by unprotected anal or vaginal intercourse, as it can be detected in fluid samples from the penis, rectum and vagina.
So far it has not been detected in fluid samples from the throat. MG, like other sexually transmitted infections STIscan cause inflammation of delicate genital tissue.
Several Mycoplasma genitalium sexually transmitted infection have found that rates of MG infection tend to be greater among people who seek care for STIs.
Urethritis is an inflammation of the tube urethra that carries urine out of the body. Common causes
Mycoplasma genitalium sexually transmitted infection urethritis are chlamydia and gonorrhea.
However, testing of urine and other samples can fail to detect possible causes of urethritis. In women, MG can cause inflammation of the urethra and cervix cervicitis and likely the uterus and the fallopian tubes.
MG is difficult to grow on a culture in the laboratory, meaning that many patients with an MG infection will have false-negative results for their culture. Some labs may have access to specialized tests that can multiply and then detect the genetic material or DNA of MG.
Such tests are called nucleic acid amplification tests NAAT. Here are several studies that sought to assess the incidence new cases, usually with symptoms and prevalence existing cases of MG among men in high-income countries:. Here are several studies that sought to assess the incidence new cases, usually with symptoms and Mycoplasma genitalium sexually transmitted infection existing cases of MG among women in high-income countries:.
Regimens for the treatment of MG can vary depending on the region or medical centre and the severity of the disease.
In clinical trials comparing the antibiotics azithromycin and doxycycline, azithromycin resulted in more cures. However, those trials were done several years ago and since then MG may have acquired more tolerance and even resistance to azithromycin.
Based on reports and clinical trials, there are at least two possible regimens of "Mycoplasma genitalium sexually transmitted infection" that doctors can consider, as follows:. Unfortunately, these two regimens have not been compared against each other in clinical trials so doctors are not certain if one is better than the other.
There is also a 2-gram, extended-release formulation of azithromycin sold as Zmax SR by Pfizer. However, no data on the effectiveness of this dose on MG has been reported. Increasingly, there have been reports of treatment failure when a single 1-gram dose of azithromycin is used in MG infection.
In such cases, some STI experts suggest the use of another antibiotic, moxifloxacin Aveloxgiven as mg once daily for between seven to 10 days. However, it is important to note that reports of MG resistant to both azithromycin and moxifloxacin have been documented. We thank Marc Steben M. The content on this page is free of advertiser influence and was produced by our editorial team.
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